Methodology
Your blood report is ranked by health impact, not alphabet. Here is exactly how — and what sits behind every recommendation.
Lab reports tell you what is flagged. They do not tell you what to act on first, or why it matters for you specifically. Two people with the same LDL reading can have very different risk profiles depending on age, family history, and other markers. FixFirst accounts for that.
Under the hood
Extract
Your PDF is read by AI. We identify biomarker names, values, units, and any lab flags — nothing else. The file is processed in memory and never stored.
Correct
Raw lab flags are a starting point, not the final word. We apply clinical corrections — a TSH of 5.2 is treated differently at 35 vs 68. HDL thresholds differ by sex. Creatinine is interpreted against activity level. This is where standard tools miss things.
Rank
Each marker is evaluated across multiple clinical dimensions — how much it affects long-term health, how concrete it is, and how your personal context shifts its urgency. The top 3 are surfaced. The methodology traces back to published guidelines; the exact weighting is not shown.
Consolidate
Flagged markers often share a cause. When 2 or more are flagged, FixFirst maps every recommendation to all the markers it moves and leads with the changes that reach the most, so 5 flags don’t turn into 5 separate protocols.
Clinical foundations
The guidelines behind the rankings
When FixFirst flags something, it is because a major clinical body says it warrants attention.
ADA Standards of Care 2024
Diabetes, prediabetes, HbA1c thresholds
ACC/AHA Cholesterol Guidelines
LDL, HDL, triglycerides, cardiovascular risk
KDIGO Clinical Practice Guidelines
Kidney function, eGFR, CKD staging
ATA Clinical Practice Guidelines
Thyroid function, TSH thresholds by age
Endocrine Society Guidelines
Vitamin D, hormones, metabolic markers
European Heart Journal
Homocysteine, hs-CRP, cardiovascular risk markers
Homocysteine Studies Collaboration
Observational risk associations for homocysteine
British Society for Haematology
CBC, haemoglobin, ferritin, iron studies
NIH / NLM Reference Ranges
General biomarker reference thresholds
Thresholds are context-aware, not just reference ranges. A TSH of 5.2 carries different clinical weight at 35 vs 68. HDL cut-offs differ by sex. Borderline markers with relevant family history are treated with appropriate urgency.
Scope
What it does
Extracts and ranks your biomarker values
Applies context-aware clinical corrections
Explains each priority in plain English
Suggests evidence-backed protocol steps
Updates rankings based on your profile
What it doesn't do
Diagnose any condition
Account for medications you take
See trends across multiple tests
Replace a conversation with your doctor
Store or retain any of your data
How to verify the output
Every recommendation in your results traces to a published guideline. If a ranking surprises you, take the marker name to your GP — they can confirm or clarify with your full medical history, medication list, and clinical context.
Who built it
FixFirst was built independently — no VC funding, no institutional affiliation, no commercial interest in your health decisions. The clinical methodology and guideline thresholds have been reviewed by a practicing physician to ensure they are grounded in current evidence.
Walk through a real example — three ranked priorities with full explanations and protocol steps.