Bryan Johnson's Blood Test Panel & Targets

Q: What blood tests does Bryan Johnson recommend?

Independent breakdowns of Johnson's Blueprint protocol consistently report targets for HbA1c, fasting insulin, ApoB, hs-CRP, vitamin D, and ferritin, among the 100+ biomarkers his panel tests. Blueprint's own public site lists the categories tested but doesn't publish an official target table, so the specific numbers here come from third-party analysis of his reported results, cross-checked across sources.

Q: How does Bryan Johnson's ferritin target differ from other longevity protocols?

It's lower, deliberately. Rhonda Patrick targets 50–100 ng/mL, treating that as the range where iron-deficiency symptoms resolve without tipping into oxidative-stress risk. Johnson's reported target of 30–60 µg/L sits lower, on the reasoning that excess stored iron accelerates oxidative damage via the Fenton reaction — the same mechanism Patrick cites for her own upper caution threshold, applied more aggressively at the low end.

Q: Is Bryan Johnson's ApoB target lower than Peter Attia's?

Reported figures put it there, yes — the mid-to-high 50s mg/dL versus Attia's stated <65 mg/dL target. Neither Blueprint nor Attia publishes these as directly comparable clinical guidance; both are individual targets cited by each person for their own protocol, not a guideline either recommends universally.

Q: Can my regular doctor order these tests?

HbA1c, fasting glucose, and vitamin D are commonly included on a standard panel. ApoB, hs-CRP, and fasting insulin usually need to be requested specifically, since they aren't part of a default lipid or metabolic panel. Insurance coverage for the less-common markers varies by provider.

Bryan Johnson's Blood Test Panel: The Markers Blueprint Targets and Why

Bryan Johnson's Blueprint protocol runs over 100 biomarkers, but Blueprint's own site doesn't publish a public table of exact target numbers. Below are six core markers with targets reported consistently across independent breakdowns of his results, each attributed to its source rather than presented as official Blueprint guidance.

AI-curated · Expert-attributed

Compiled by AI from the named experts’ own public statements, with every figure attributed to its source. These are individual expert protocols, not clinical guidelines or FixFirst medical advice. Evidence & methodology

6 markers, cross-checked across independent sources Every target attributed and sourced, not invented Free 45-second read on your own results

Why there's no official target table

Blueprint's public biomarkers page (blueprint.bryanjohnson.com/pages/biomarkers) lists the categories of markers tested — over 100 across blood and urine — but does not publish Johnson's personal target numbers. The figures below come from independent breakdowns of his publicly reported results, cross-checked against at least two sources per marker.

This page is part of FixFirst's Longevity blood markers series, which attributes every target to the person who cited it rather than presenting it as clinical guidance. Where independent sources reported different exact figures for the same marker (common with Johnson's numbers, since they come from third-party analysis rather than an official published table), the range below reflects that spread instead of picking one number arbitrarily.

Some markers below (HbA1c, fasting glucose, vitamin D, ferritin) are commonly included on a standard panel. Others (ApoB, hs-CRP, fasting insulin) usually need to be requested specifically, the same gap covered generally in the optimal vs. normal ranges guide.

The 6 core markers

Grouped by system: metabolic health, cardiovascular/inflammation, and nutrient status.

Cluster 1 of 3

Metabolic health

Johnson treats HbA1c and fasting insulin as a pair rather than reading either alone — the same logic Attia and other longevity clinicians apply, since fasting insulin can flag resistance while HbA1c and glucose are still in range.

Core Usually in a standard panel Ask Request specifically

Core

HbA1c

Reported target around 5.0–5.2%, tighter than the ADA prediabetes threshold of 5.7% and tighter than Peter Attia's own <5.5% target.

Ask

Fasting Insulin

Reported target under 5–6 µIU/mL, well under the standard lab ceiling of 25 µIU/mL, treated as part of the same metabolic cluster as HbA1c rather than in isolation.

Cluster 2 of 3

Cardiovascular & inflammation

Johnson weights ApoB and hs-CRP heavily in his risk model, targeting both below the ranges cited by other longevity-focused protocols on this site.

Core Usually in a standard panel Ask Request specifically

Ask

ApoB

Reported target in the mid-to-high 50s mg/dL, below Peter Attia's own <65 mg/dL target and well under the standard guideline threshold of <100 mg/dL.

Ask

hs-CRP

Reported target well under 0.5 mg/L, tighter than Attia's and Tim Ferriss's own <1.0 mg/L targets and far under the standard clinical flag of 3.0 mg/L.

Cluster 3 of 3

Nutrient status

Johnson's approach to ferritin is a notable departure from other longevity protocols on this site: where Rhonda Patrick targets a higher 50–100 ng/mL band, Johnson deliberately targets lower, citing the same oxidative-stress mechanism she uses to justify her own upper caution threshold.

Core Usually in a standard panel Ask Request specifically

Core

Vitamin D

Reported target of 40–60 ng/mL, the same range cited by Rhonda Patrick and well above the standard lab deficiency floor of 20–30 ng/mL.

Ask

Ferritin

Reported target of 30–60 µg/L — deliberately lower than the 50–100 ng/mL range other longevity protocols on this site target, reasoning that excess stored iron drives oxidative stress via the Fenton reaction.

Frequently asked questions

What blood tests does Bryan Johnson recommend?

Independent breakdowns of Johnson's Blueprint protocol consistently report targets for HbA1c, fasting insulin, ApoB, hs-CRP, vitamin D, and ferritin, among the 100+ biomarkers his panel tests. Blueprint's own public site lists the categories tested but doesn't publish an official target table, so the specific numbers here come from third-party analysis of his reported results, cross-checked across sources.

How does Bryan Johnson's ferritin target differ from other longevity protocols?

It's lower, deliberately. Rhonda Patrick targets 50–100 ng/mL, treating that as the range where iron-deficiency symptoms resolve without tipping into oxidative-stress risk. Johnson's reported target of 30–60 µg/L sits lower, on the reasoning that excess stored iron accelerates oxidative damage via the Fenton reaction — the same mechanism Patrick cites for her own upper caution threshold, applied more aggressively at the low end.

Is Bryan Johnson's ApoB target lower than Peter Attia's?

Reported figures put it there, yes — the mid-to-high 50s mg/dL versus Attia's stated <65 mg/dL target. Neither Blueprint nor Attia publishes these as directly comparable clinical guidance; both are individual targets cited by each person for their own protocol, not a guideline either recommends universally.

Can my regular doctor order these tests?

HbA1c, fasting glucose, and vitamin D are commonly included on a standard panel. ApoB, hs-CRP, and fasting insulin usually need to be requested specifically, since they aren't part of a default lipid or metabolic panel. Insurance coverage for the less-common markers varies by provider.

Once you have your results

These are reported targets from one individual's protocol, not a clinical guideline. Seeing where your own results sit against the standard clinical range is the first comparison point.

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More longevity marker pages

See the full Longevity section

Peter Attia's panel, Andrew Huberman's markers, and optimal IGF-1, each attributed to its source.

Browse the Longevity section

Bryan Johnson's Blood Test Panel: The Markers Blueprint Targets and Why

Why there's no official target table

The 6 core markers

Frequently asked questions

Once you have your results

See where your results land against the standard clinical ranges.