Hair loss has multiple treatable causes, iron depletion, thyroid dysfunction, hormonal shifts, and nutritional gaps, most of which won't show on a standard annual panel. Here are the specific tests to request, organised by cause.
A routine CBC and metabolic panel screens for disease. it is not designed to investigate hair loss as a symptom.
When you go to your doctor concerned about hair shedding, you'll typically receive a standard blood count and perhaps a single TSH test. This is a reasonable starting point, but it leaves several major causes uninvestigated.
A CBC measures haemoglobin, which only drops after iron stores are already severely depleted. It does not include ferritin — the iron storage protein that many dermatologists regard as the single most important blood test in a hair loss workup. A standard TSH measures the pituitary's signal to the thyroid, but does not include free T3, free T4, or TPO antibodies — all of which are relevant when thyroid-driven hair loss is suspected. And hormonal causes, elevated androgens, low SHBG, and PCOS require specific tests that are almost never part of a routine annual panel.
The four cause clusters below are what a thorough hair loss investigation actually covers. Not every cluster applies to every person, the hormonal cluster, in particular, differs significantly between men and women, but knowing which tests exist and what to ask for puts you in a much better position.
Organised by cause. Each cluster lists tests your panel should include, and additional tests worth requesting specifically.
This is the most common reason a hair loss workup comes back "all clear" when it shouldn't. A standard lab flags ferritin as low only below 12–15 ng/mL. Most clinical labs define "normal" as anything above that threshold, which means a ferritin of 16 ng/mL gets a green tick on your report.
Research by Rushton et al. (Journal of Cosmetic Dermatology, 2002) found that ferritin below 40 μg/L was significantly more common in women with unexplained diffuse hair loss compared to controls with no hair loss. Most dermatologists who specialise in hair loss use a functional target of 40–70 ng/mL, levels well above the standard lab flagging threshold but where iron stores are genuinely adequate for hair follicle function.
If your ferritin came back "normal" at 18–30 ng/mL, discuss with your doctor whether iron repletion is appropriate given your symptoms. This is not the same as having anaemia, haemoglobin can be completely normal while ferritin remains in a range that may not support optimal hair growth.
Most GPs order what a standard protocol recommends. Being specific about what you want, and why, changes the outcome.
Getting the right tests ordered is step one. Reading the results properly is step two.
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